Rhine Repose with Switzerland, France, Germany & Holland

There's a point where Switzerland, Germany, and France meet—that point is the Swiss city of Basel. By the Middle Ages, Basel was a center of culture and commerce, and by the 15th century, it was an epicenter for the printing industry. In fact, it was here that the world's first printed book was published. Today, Basel is known for its pharmaceutical industry, exciting art scene, impressive 13th-century Gothic cathedral, and its annual Carnival celebrations that attract visitors from around the world each February.

If your travel Bucket List doesn't include Strasbourg, it should! From the stunning gardens of Parc de l'Orangerie to the European Quarter, there's something to see in every direction. This is where the EU Parliament, Council of Europe, and other international institutions are based, and where the Grande Île, the Old Town island framed by two river arms, leaves an unforgettable impression. The pink sandstone cathedral with its famous astronomical clock and canal-lined Petite France district are the very definition of Old World European magic.

Deep in the heart of the Rhine Gorge is the romantic wine village of Rüdesheim, one of the river's most popular ports. Home to some of Germany's finest vineyards, Rüdesheim is particularly famous for its Riesling, as well as its signature coffee made with German brandy, whipped cream, and chocolate shavings. Highlight attractions include the cable car up to the Niederwald Monument, which commemorates the unification of Germany in 1871, and the atmospheric Drosselgasse, lined with gorgeous Old World architecture, boutiques, and countless cozy wine taverns.

What do the Romans, Johannes Gutenberg, medieval Ashkenazi Jews, the French revolutionary army, WWII air raids, and Carnival have in common? Their associations with Mainz! The Old Town's narrow, winding lanes pass by the places where 2,000 years of history have been written: half-timbered and patrician houses, the 13th-century Iron Tower, Electoral Palace, and thousand-year-old Mainz Cathedral. In addition to the historical, also has a long tradition of wine cultivation, so sampling a glass is a wonderful idea!

Mainhattan—it's a nickname that Frankfurt am Main has earned as home to more than 300 international credit institutions, the European Central Bank, and the Frankfurt Stock Exchange. But today's bustling city has humble roots reaching back over 2,000 years, and a turbulent fate during WWII that saw bombing of much of its historic architecture. Post-war, Frankfurt rebuilt and is now a blend of modern skyscrapers and rebuilt treasures.

Koblenz, founded by the Romans as Confluentes (‘confluence of two rivers’), lies at the meeting point of the Rhine and Moselle. Its strategic position made it both a thriving trade hub and the site of frequent battles, prompting the construction of strong medieval fortifications that can still be seen today. Visitors are drawn to its river scenery, the mighty Ehrenbreitstein Fortress, the Deutsches Eck monument, and the charming Old Town with its half-timbered houses

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With just 5,000 residents, Cochem could easily be mistaken for a sleepy village, but this Moselle gem is full of surprises! From the ancient gate and old watchtower to the market square lined with half-timber houses, there's something to see in every direction! There's plenty of scenic beauty during riverbank strolls and vineyard hikes. Highlights include the hilltop castle dating back to 1000 AD and the chance to sample the red Moselle vineyard peach, the juicy "Persian apple" the Romans brought to the area in ancient times!

The electric atmosphere of 2,000-year-old Cologne is undeniable. Its strategic location on the Rhine quickly elevated the city as a vital trade center that grew into a hub of industry by the 19th century. Even plagues and wars couldn't damper Cologne's tenacious spirit. During WWII, nearly 90% of the city center was destroyed, but a massive rebuilding effort restored much of its cultural heritage, including its famous Gothic cathedral. Highlights include the four preserved gates in the city wall, and Kölsch—the beer that’s been brewed here since the 17th century!

Proud international hub of business and finance, Düsseldorf is ranked the sixth-most-livable city in the world, but it wasn't always this way. It started as the marshland home of Germanic tribes before small farming and fishing settlements began cropping up in the 7th century. Today's highlights include the harbor, Gothic St. Lambertus Church with its twisted tower, the palace tower, and Germany's oldest inland navigation museum. Meanwhile, the 200-year Altbier tradition makes a taste of the copper-colored brew feel like sipping a piece of history.

One of the Netherlands' oldest cities, Nijmegen recently celebrated its 2,000th birthday! Located near the German border, it was the first Dutch city to fall into German hands during WWII and heavy bombings left Nijmegen with few remaining historic buildings. Among its treasures, though, are Valkhof Park, site of a palace ruin whose construction was started by Charlemagne in the 8th century; the 16-sided Sint Nicolaas Chapel; and De Waagh (weigh house), built in 1612 in the Dutch Renaissance style and still sporting a huge set of scales hanging inside the building.

Capital of the Netherlands, the magical Venice of the North is famous for its dazzling Golden Age of power and wealth during the 16th and 17th centuries. Today, it is a bustling wonderland of things to see and do. No visit is complete without a cruise along the intricate network of more than 62 miles (100 km) of canals and time with the Dutch masters at the renowned Rijksmuseum. Other highlights include the Royal Palace, Anne Frank House, lavish 17th-century canal homes, Heineken Beer Experience, and the infamous red-light district!